[New paper] CLEMENT: Algorithm for accurate decomposition of non-tumor diploid samples
- sak042
- Jun 26, 2024
- 1 min read
Updated: Sep 21
Our new paper published in Nucleic Acids Research.
In this paper, Young-soo Chung and Seungseok Kang present CLEMENT, a novel tool applicable to clonal decomposition in DNA bulk sequencing data, specifically designed for non-tumor diploid samples.
Congratulations!
Young-soo Chung, Seungseok Kang, Jisu Kim, Sangbo Lee, Sangwoo Kim, CLEMENT: genomic decomposition and reconstruction of non-tumor subclones, Nucleic Acids Research, 2024;, gkae527, https://doi.org/10.1093/nar/gkae527
![[Media cover] Dr. Junho Kim appeared in BRIC homepage](https://static.wixstatic.com/media/445be0_92e55fd8503243c0b39bd11e32b70c78~mv2.png/v1/fill/w_870,h_486,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/445be0_92e55fd8503243c0b39bd11e32b70c78~mv2.png)
![[Media cover] Dr. Junho Kim appeared in BRIC homepage](https://static.wixstatic.com/media/445be0_92e55fd8503243c0b39bd11e32b70c78~mv2.png/v1/fill/w_870,h_486,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_92e55fd8503243c0b39bd11e32b70c78~mv2.png)
![[New paper] New model for calling low-level somatic mutations](https://static.wixstatic.com/media/445be0_98fe336b355d4de7969f74b807056e1d~mv2.png/v1/fill/w_628,h_351,fp_0.50_0.50,lg_1,q_35,blur_30,enc_avif,quality_auto/445be0_98fe336b355d4de7969f74b807056e1d~mv2.png)
![[New paper] New model for calling low-level somatic mutations](https://static.wixstatic.com/media/445be0_98fe336b355d4de7969f74b807056e1d~mv2.png/v1/fill/w_628,h_351,fp_0.50_0.50,lg_1,q_95,enc_avif,quality_auto/445be0_98fe336b355d4de7969f74b807056e1d~mv2.png)
![[Award] Prof. Sangwoo Kim won the 5th Amgen-KAST Biotechnology Award from the Korean Academy of Science and Technology (KAST)](https://static.wixstatic.com/media/445be0_6a700e498873459eac095d6931050fac~mv2.jpg/v1/fill/w_761,h_432,fp_0.50_0.50,lg_1,q_30,blur_30,enc_avif,quality_auto/445be0_6a700e498873459eac095d6931050fac~mv2.jpg)
![[Award] Prof. Sangwoo Kim won the 5th Amgen-KAST Biotechnology Award from the Korean Academy of Science and Technology (KAST)](https://static.wixstatic.com/media/445be0_6a700e498873459eac095d6931050fac~mv2.jpg/v1/fill/w_296,h_168,fp_0.50_0.50,q_90,enc_avif,quality_auto/445be0_6a700e498873459eac095d6931050fac~mv2.jpg)
![[Award] Taehyeon Kim won BIOINFO 2025 Excellent Poster Award from the Korean Society for Bioinformatics (KSBI)](https://static.wixstatic.com/media/445be0_d28d626f4324465c9e9a51a67131f94a~mv2.jpg/v1/fill/w_1000,h_1000,fp_0.50_0.50,q_30,blur_30,enc_avif,quality_auto/445be0_d28d626f4324465c9e9a51a67131f94a~mv2.jpg)
![[Award] Taehyeon Kim won BIOINFO 2025 Excellent Poster Award from the Korean Society for Bioinformatics (KSBI)](https://static.wixstatic.com/media/445be0_d28d626f4324465c9e9a51a67131f94a~mv2.jpg/v1/fill/w_296,h_296,fp_0.50_0.50,q_90,enc_avif,quality_auto/445be0_d28d626f4324465c9e9a51a67131f94a~mv2.jpg)
![[News] Celebrating Our Alumna: Dr. Yoo-Jin Ha Joins Hanyang University as a Professor](https://static.wixstatic.com/media/445be0_f9868047493140be95e8d6d45b574425~mv2.png/v1/fill/w_547,h_481,fp_0.50_0.50,lg_1,q_35,blur_30,enc_avif,quality_auto/445be0_f9868047493140be95e8d6d45b574425~mv2.png)
![[News] Celebrating Our Alumna: Dr. Yoo-Jin Ha Joins Hanyang University as a Professor](https://static.wixstatic.com/media/445be0_f9868047493140be95e8d6d45b574425~mv2.png/v1/fill/w_296,h_260,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_f9868047493140be95e8d6d45b574425~mv2.png)
![[Award] Ahyeon Kim won the Research Support Scholarship from the Health Fellowship Foundation (HFF)](https://static.wixstatic.com/media/445be0_eed364dcfe4047dfa6644808d046c2bb~mv2.png/v1/fill/w_171,h_224,fp_0.50_0.50,lg_1,q_35,blur_30,enc_avif,quality_auto/445be0_eed364dcfe4047dfa6644808d046c2bb~mv2.png)
![[Award] Ahyeon Kim won the Research Support Scholarship from the Health Fellowship Foundation (HFF)](https://static.wixstatic.com/media/445be0_eed364dcfe4047dfa6644808d046c2bb~mv2.png/v1/fill/w_171,h_224,fp_0.50_0.50,lg_1,q_95,enc_avif,quality_auto/445be0_eed364dcfe4047dfa6644808d046c2bb~mv2.png)
![[Media cover] Taek Chung’s research covered in media](https://static.wixstatic.com/media/445be0_e2366087f3ee42dbb47a742af6016908~mv2.png/v1/fill/w_766,h_435,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/445be0_e2366087f3ee42dbb47a742af6016908~mv2.png)
![[Media cover] Taek Chung’s research covered in media](https://static.wixstatic.com/media/445be0_e2366087f3ee42dbb47a742af6016908~mv2.png/v1/fill/w_296,h_168,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_e2366087f3ee42dbb47a742af6016908~mv2.png)
![[New paper] Carcinogenic sequence uncovered at the genomic and transcriptomic levels in biliary tract cancer](https://static.wixstatic.com/media/445be0_71f38d7e682142adb88dfc5102a6c73d~mv2.png/v1/fill/w_474,h_269,fp_0.50_0.50,lg_1,q_35,blur_30,enc_avif,quality_auto/445be0_71f38d7e682142adb88dfc5102a6c73d~mv2.png)
![[New paper] Carcinogenic sequence uncovered at the genomic and transcriptomic levels in biliary tract cancer](https://static.wixstatic.com/media/445be0_71f38d7e682142adb88dfc5102a6c73d~mv2.png/v1/fill/w_296,h_168,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_71f38d7e682142adb88dfc5102a6c73d~mv2.png)
![[Published in Nature] Meningomyelocele Linked to De Novo Genetic Mutations, According to Landmark Study](https://static.wixstatic.com/media/445be0_20fa3d5737964fdcbf6a1f0a0dc2eceb~mv2.png/v1/fill/w_1762,h_1000,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/445be0_20fa3d5737964fdcbf6a1f0a0dc2eceb~mv2.png)
![[Published in Nature] Meningomyelocele Linked to De Novo Genetic Mutations, According to Landmark Study](https://static.wixstatic.com/media/445be0_20fa3d5737964fdcbf6a1f0a0dc2eceb~mv2.png/v1/fill/w_296,h_168,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_20fa3d5737964fdcbf6a1f0a0dc2eceb~mv2.png)
![[New paper] Reversion of BRCA1 L1780P mutation confers resistance to PARP and ATM inhibitors in breast cancer](https://static.wixstatic.com/media/445be0_c80a6fb2c75e474a80d7882264800d60~mv2.png/v1/fill/w_996,h_996,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/445be0_c80a6fb2c75e474a80d7882264800d60~mv2.png)
![[New paper] Reversion of BRCA1 L1780P mutation confers resistance to PARP and ATM inhibitors in breast cancer](https://static.wixstatic.com/media/445be0_c80a6fb2c75e474a80d7882264800d60~mv2.png/v1/fill/w_296,h_296,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_c80a6fb2c75e474a80d7882264800d60~mv2.png)
![[Award] Yoo-Jin Ha awarded The 14th Dissertation of the Year Award (Biological Science) from the Korean Academy of Science and Technology, funded by The S-OIL Science and Culture](https://static.wixstatic.com/media/445be0_c83776be76b64949bae81e77ed5433de~mv2.png/v1/fill/w_956,h_620,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/445be0_c83776be76b64949bae81e77ed5433de~mv2.png)
![[Award] Yoo-Jin Ha awarded The 14th Dissertation of the Year Award (Biological Science) from the Korean Academy of Science and Technology, funded by The S-OIL Science and Culture](https://static.wixstatic.com/media/445be0_c83776be76b64949bae81e77ed5433de~mv2.png/v1/fill/w_296,h_192,fp_0.50_0.50,q_95,enc_avif,quality_auto/445be0_c83776be76b64949bae81e77ed5433de~mv2.png)
![[Award] Jeongsoo Won won best poster award in BIOINFO 2024](https://static.wixstatic.com/media/445be0_c70a449b1e73476fb55ac9955da13682~mv2.jpg/v1/fill/w_1000,h_1000,fp_0.50_0.50,q_30,blur_30,enc_avif,quality_auto/445be0_c70a449b1e73476fb55ac9955da13682~mv2.jpg)
![[Award] Jeongsoo Won won best poster award in BIOINFO 2024](https://static.wixstatic.com/media/445be0_c70a449b1e73476fb55ac9955da13682~mv2.jpg/v1/fill/w_296,h_296,fp_0.50_0.50,q_90,enc_avif,quality_auto/445be0_c70a449b1e73476fb55ac9955da13682~mv2.jpg)
