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Se-Young Jo

  CONTACT INFORMATION  

Translational Genome Informatics Laboratory

Dept. of Biomedical Systems Informatics

Yonsei University College of Medicine

#616 College of Medicine Bldg, 50-1 Yonsei-ro, Seodaemun-gu,

Seoul 03722, South Korea.

Office: +82-2-2228-2487

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  EDUCATION & EXPERIENCE  

  • PostDoc Researcher, Yonsei University College of Medicine, 2023 - present

  • Visiting Graduate Student, University of California San Diego, 2022 - 2023

  • Graduate Researcher & Teaching Assistant, Yonsei University College of Medicine, 2021 - 2022

  • Integrated M.S. & Ph.D. in Medical Science, Yonsei University College of Medicine, 2017 - 2023
    (Thesis : Genome-wide profiling of     allele-specific expression in cancer)

  • B.S. Researcher, Asan Biomedical Research Center, Asan Medical Center, 2014 - 2017

  • B.S. in Biology, Yonsei University College of Science, Seoul, Korea, 2003 - 2009​

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  PUBLICATIONS  

Journal Papers (Peer reviewed)

    † These authors contributed equally to this work.

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  1. Yoo-Jin Ha, Seungseok Kang, Jisoo Kim, Junhan Kim, Se-Young Jo, Sangwoo Kim, Comprehensive benchmarking and guidelines of mosaic variant calling strategies, Nature Methods 2023

  2. Se-Young Jo†, Namki Hong†, Seunghyun Lee, Jong Ju Jeong, Jeongsoo Won, Jiho Park, Kijung Kim, Sang Kyum Kim, Sangwoo Kim, Yumie Rhee, Genomic and transcriptomic profiling reveal molecular characteristics of parathyroid carcinoma, Experimental & Molecular Medicine 55, 886-897, 2023 

  3. Hee Seung Lee†, Eunyoung Kim†, Jinyoung Lee, Seung Joon Park, Ho Kyoung Hwang, Chan Hee Park, Se-Young Jo, Chang Moo Kang, Seung-Mo Hong, Huapyong Kang, Jung Hyun Jo, In Rae Cho, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Jung Min Han, Sangwoo Kim, and Seungmin Bang, Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer, EBioMedicine 65 (103218), 2021

  4. Se-Young Jo, Eunyoung Kim, Sangwoo Kim, Impact of mouse contamination in genomic profiling of patient-derived model and best practice for robust analysis, Genome Biology 20, 231, 2019

  5. Ai NH Phan, Vu TA Vo, Tuyen NM Hua, Min-Kyu Kim, Se-Young Jo, Jong-Whan Choi, Hyun-Won Kim, Jaekyoung Son, Young-Ah Suh, Yangsik, Jeong, PPARγ sumoylation-mediated lipid accumulation in lung cancer, Oncotarget 2017, 8 (47), 82491

  6. Dong Woo Kang, Eun Sun Yang, Yu Na Noh, Won Chan Hwang, Se‐Young Jo, Young‐Ah Suh, Won Sang Park, Kang‐Yell Choi, Do Sik Min, MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting β‐catenin and ATP‐binding cassette, subfamily G, member 2, The Journal of Pathology 2017, 241 (5), 614-625

  7. Chae Lim Jung, Hyemin Mun, Se-Young Jo, Ju-Hee Oh, ChuHee Lee, Eun-Kyung Choi, Se Jin Jang, Young-Ah Suh, Suppression of gain-of-function mutant p53 with metabolic inhibitors reduces tumor growth in vivo, Oncotarget 2016, 7 (47), 77664

  8. So Jung Park, Doo Sin Jo, Se-Young Jo, Dong Woon Shin, Sangmi Shim, Yoon Kyung Jo, Ji Hyun Shin, Ye Jin Ha, Seong-Yun Jeong, Jung Jin Hwang, Young Sam Kim, Young-Ah Suh, Jong Wook Chang, Jin Cheon Kim, Dong-Hyung Cho, Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death, Oncotarget 2016, 7 (40), 65957

  9. Young-Ah Suh, Se-Young Jo, Hwa-Young Lee, Chuhee Lee, Inhibition of IL-6/STAT3 axis and targeting Axl and Tyro3 receptor tyrosine kinases by apigenin circumvent taxol resistance in ovarian cancer cells, International Journal of Oncology 2015, 46 (3), 1405-1411

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Journal Papers (in preparation)

    † These authors contributed equally to this work.

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  1. Se-Young Jo†, Jeong Dong Lee†, Jeongsoo Won, Jiho Park, Taeyong Kwon, Joohyuk Sohn, Sueng-Il Kim, Sangwoo Kim, Hyung Seok Park, Reversion of pathogenic BRCA1 L1780P mutation confers resistance to PARP and ATM inhibitor in breast cancer (In preparation)

  2. Miin S Lin, Se-Young Jo, Jens Luebeck, Howard Y Chang, Sihan Wu, Paul S Mischel, Vineet Bafna, Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors (In preparation)

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CONFERENCES AND SEMINARS

International Conferences

  1. Poster presentation on AGBT Precision Health 2022, San Diego, CA, US, Transcriptomic profiling of parathyroid tumors reveals distinctive molecular characteristics of carcinoma and adenoma

  2. Poster presentation on RECOMB 2022, La Jolla, CA, US, Transcriptomic profiling of parathyroid tumors reveals distinctive molecular characteristics of carcinoma and adenoma

  3. Oral presentation on BIOINFO 2020, Seoul, Korea, Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis

  4. Poster presented on AGBT Precision Health 2019, La Jolla, CA, US, Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis

  5. Poster presented on BIOINFO 2019, Seoul, Korea, Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis

  6. Poster presented on 6th Yu Il-han Biomedical Forum 2019, Seoul, Korea, Systematic assessment of mouse read filtration pipeline and the impacts on genomic analysis in xenograft sequencing

  7. Attended and Survived the Cold Spring Harbor Course on Organotypic & Next Generation Culture Methods, Dec. 1st ~ 14th, 2016, Laurel Hollow, NY, US

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  AWARDS  ​

  • Academic Award for Excellence, Yonsei University College of Medicine, 2023

  • Best Presentation Award, Brain Korea 21 PLUS Project, Yonsei University College of Medicine, 2023

  • Standigm Best Paper Award, Korean Society for Bioinformatics, 2020

  • Best Research Article Award, Yonsei University, 2020

  • Academic Award for Excellence, Biomedical Systems Informatics, Yonsei University College of Medicine, 2019

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  FUNDING GRANTED  ​

  • Postdoctoral Domestic Training Support Program 2023-2024, National Research Foundation of Korea (NRF), USD 46,000

  • Biomedical Global Talent Nurturing Program (Ph.D. Course) 2022, Korea Health Industry Development Institute, USD 64,000

  • Brain Korea 21 Scholarship 2017-2023 (full tuition), Brain Korea 21 Project, Yonsei University College of Medicine

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  SKILLS  

Computer

  • NGS data analysis

  • Computational language: Python, R, Bash

  • Imaging: Illustrator, Photoshop

  • Text: Word, LaTeX

  • Data: Excel, Prism

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Biology

  • Molecular: DNA/RNA handling, RT-PCR

  • Biochemistry: protein analysis, protein purification

  • Cell culture: primary cell culture, stable cell-line culture, conditionally-reprogrammed cell culture, organoid culture, virus handling

  • Animal: mouse handling and surgery

  • Histology: immunohistochemical staining

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Last Update: December 1, 2023

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