Mi-kyoung Seo, M.S.
CONTACT INFORMATION
Translational Genome Informatics Laboratory
Dept. of Biomedical Systems Informatics
Yonsei University College of Medicine
50-1 Yonsei-ro, Seodaemun-gu,
Seoul 03722, South Korea.
Office: +82-2-2228-2487
RESEARCH AREAS
Translational medical research, Cancer research, Bioinformatics, Classification, Machine learning, Clonal analysis
EDUCATION
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Mar. 2013. ~ Present Yonsei University College of Medicine, Seoul, Korea
Dept. of Biomedical Systems Informatics,
Ph.D Candidate
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Sept. 2012 ~ Aug. 2014 Ajou University, Suwon, Korea
Biomedical Science
Master of Science in Biomedical Science
Thesis: An Efficient Clustering Algorithm for Categorical Data Sets
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Mar. 2004 ~ Feb. 2007 Ajou University, Suwon, Korea
Bachelor of Science in Biological Sciences
RESEARCH EXPERIENCES
1. Molecular Heterogeneity of Microsatellite instability of Colorectal cancer
2. miniABS: an absolute, single-sample subtype classifier of breast cancer
with 11 functional genes
Classification using machine learning
3. Fusion gene of Bile duct cancer
4. Mendelian disease analysis using WGS and RNA-seq
5. CMS classifier based on expression and tumor microenvironment
PUBLICATIONS
Journal Publications
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Won-Ji Ryu, Jae Eun Lee, Yong-Hee Cho, Gunho Lee, Mi-kyoung Seo, Sang-Kyu Lee, Jeong-Ha Hwang, Do Sik Min, Sung Hoon Noh, Soonmyung Paik, Sangwoo Kim, Jae-Ho Cheong*, and Kang-Yell Choi*, A therapeutic Strategy for chemotherapy-resistant gastric cancer via destabilization of both b-catenin and RAS, Cancers, 2019(11):4, 496
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Gunho Lee†, Hyang Joo Ryu†, Ji Woon Choi, Hyundeok Kang, Woo Ick Yang, In Seok Yang, Mi-Kyoung Seo, Sangwoo Kim* and Sun Och Yoon*, Characteristic gene alterations in primary gastrointestinal T and NK cell lymphomas, Leukemia 2019 (Epub ahead of print)
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Jung-Sub Park, Seo-Jun Kang, Mi-kyoung Seo, Ilo Jou, Hyun Goo Woo, and Sang Myun Park, Role of cysteinyl leukotriene signaling in a mouse model of noise-induced cochlear, injury, Proc Natl Acad Sci U S A. 2014, 8;111(27):9911-6
Presentations
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miniABS: an absolute, single-sample subtype classifier of breast cancer with 11 functional genes. Poster presentation at the AACR-KCA Joint Conference, Seoul, Korea, Nov. 16, 2018
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miniABS: Absolute Subtyping of Breast Cancer with a Minimal Gene Set. Poster presentation at The 28th International Conference on Genome Informatics GIW/BIOINFO 2017, Seoul, Korea, Nov. 3, 2017
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miniABS(mini Absolute Breast Cancer Subtyper). Poster presentation at the 2nd International Oncologist & Diagnostics Conference, Brussels, Belgium, Aug. 29, 2017
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miniABS(mini Absolute Breast Cancer Subtyper). Poster presentation at The annual international conference on Ingelligent Systems for Molecular Biology, 2016, Orlando, USA, Jul. 9, 2016
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RNA-seq based Absolute Subtyping of Breast Cancer. Poster presentation at the BIOINFO 2015 "The Deep Impact: Data-driven Biology&Medicine", 2015, Oct. 22, 2015
AWARDS AND HONORS
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Nov. 2018 K-Genome Competition 2018 (The second place), Korea Genome Open HRD
Algorithm and pipeline package development for genomic data analysis
WORK EXPERIENCES
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Jul. 2014 ~ Feb. 2015 Yonsei University College of Medicine, Seoul, Korea
Translational Genome Informatics Laboratory
Researcher
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Jun. 2012 ~ Dec. 2015 Korea Institute of Science and Technology Information (KISTI)
BRIC reporter
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Nov. 2010 ~ May. 2012 R&D, Theragen Itex (Genome Research Foundation)
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Apr. 2010 ~ Oct. 2010 Bio-internship 6th, Korea Biotechnology Industry Organization
Bio-internship 6th Intern
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May 2008 ~ Jun. 2009 Quality Assurance department, WOORIDUL PHARMACEUTICAL LTD.
Quality Assurance
PATENTS
International Patents (PCT, Pending)
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“Methods for classifying breast cancer subtypes and a device for classifying breast cancer subtype using the same”, PCT/KR2017/014345
Inventor: Sangwoo Kim, Soonmyung Paik and Mi-Kyoung Seo
Domestic Patents (Issued)
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“유방암 분자아형 분류방법 및 유방암 분자아형 분류 디바이스”, 대한민국 특허 10-1966589, 2019/04/01
발명자: 김상우, 백순명, 서미경
