CONTACT INFORMATION  

Translational Genome Informatics Laboratory

Dept. of Biomedical Systems Informatics

Yonsei University College of Medicine

50-1 Yonsei-ro, Seodaemun-gu,

Seoul 03722, South Korea.

Office: +82-2-2228-2487

  RESEARCH AREAS  

Translational medical research, Cancer research, Bioinformatics, Classification, Machine learning, Clonal analysis

  EDUCATION  

  • Mar. 2013. ~ Present        Yonsei University College of Medicine, Seoul, Korea

                                                Dept. of Biomedical Systems Informatics,

                                                Ph.D Candidate

  • Sept. 2012 ~ Aug. 2014   Ajou University, Suwon, Korea

                                                Biomedical Science

                                                Master of Science in Biomedical Science

                                                     Thesis: An Efficient Clustering Algorithm for Categorical Data Sets

  • Mar. 2004 ~ Feb. 2007     Ajou University, Suwon, Korea

                                                Bachelor of Science in Biological Sciences

  RESEARCH EXPERIENCES  

1. Molecular Heterogeneity of Microsatellite instability of Colorectal cancer


2. miniABS: an absolute, single-sample subtype classifier of breast cancer

    with 11 functional genes

    Classification using machine learning


3. Fusion gene of Bile duct cancer


4. Mendelian disease analysis using WGS and RNA-seq

5. CMS classifier based on expression and tumor microenvironment

  PUBLICATIONS  

Journal Publications

  1. Won-Ji Ryu, Jae Eun Lee, Yong-Hee Cho, Gunho Lee, Mi-kyoung Seo, Sang-Kyu Lee, Jeong-Ha Hwang, Do Sik Min, Sung Hoon Noh, Soonmyung Paik, Sangwoo Kim, Jae-Ho Cheong*, and Kang-Yell Choi*, A therapeutic Strategy for chemotherapy-resistant gastric cancer via destabilization of both b-catenin and RAS, Cancers, 2019(11):4, 496

  2. Gunho Lee†, Hyang Joo Ryu†, Ji Woon Choi, Hyundeok Kang, Woo Ick Yang, In Seok Yang, Mi-Kyoung Seo, Sangwoo Kim* and Sun Och Yoon*, Characteristic gene alterations in primary gastrointestinal T and NK cell lymphomas, Leukemia 2019 (Epub ahead of print)

  3. Jung-Sub Park, Seo-Jun Kang, Mi-kyoung Seo, Ilo Jou, Hyun Goo Woo, and Sang Myun Park, Role of cysteinyl leukotriene signaling in a mouse model of noise-induced cochlear, injury, Proc Natl Acad Sci U S A. 2014, 8;111(27):9911-6

Presentations

  1. miniABS: an absolute, single-sample subtype classifier of breast cancer with 11 functional genes. Poster presentation at the AACR-KCA Joint Conference, Seoul, Korea, Nov. 16, 2018

  2. miniABS: Absolute Subtyping of Breast Cancer with a Minimal Gene Set. Poster presentation at The 28th International Conference on Genome Informatics GIW/BIOINFO 2017, Seoul, Korea, Nov. 3, 2017

  3. miniABS(mini Absolute Breast Cancer Subtyper). Poster presentation at the 2nd International Oncologist & Diagnostics Conference, Brussels, Belgium, Aug. 29, 2017

  4. miniABS(mini Absolute Breast Cancer Subtyper). Poster presentation at The annual international conference on Ingelligent Systems for Molecular Biology, 2016, Orlando, USA, Jul. 9, 2016

  5. RNA-seq based Absolute Subtyping of Breast Cancer. Poster presentation at the BIOINFO 2015 "The Deep Impact: Data-driven Biology&Medicine", 2015, Oct. 22, 2015

  AWARDS AND HONORS  

  • Nov. 2018      K-Genome Competition 2018 (The second place), Korea Genome Open HRD

                          Algorithm and pipeline package development for genomic data analysis

  WORK EXPERIENCES  

  • Jul. 2014 ~ Feb. 2015          Yonsei University College of Medicine, Seoul, Korea
                                                 Translational Genome Informatics Laboratory
                                                 Researcher

  • Jun. 2012 ~ Dec. 2015        Korea Institute of Science and Technology Information (KISTI)

                                                 BRIC reporter

  • Nov. 2010 ~ May. 2012        R&D, Theragen Itex (Genome Research Foundation)

  • Apr. 2010 ~ Oct. 2010         Bio-internship 6th, Korea Biotechnology Industry Organization

                                                 Bio-internship 6th Intern

  • May 2008 ~ Jun. 2009         Quality Assurance department, WOORIDUL PHARMACEUTICAL LTD.

                                                 Quality Assurance

  PATENTS  

International Patents (PCT, Pending)

  • “Methods for classifying breast cancer subtypes and a device for classifying breast cancer subtype using the same”, PCT/KR2017/014345
    Inventor: Sangwoo Kim, Soonmyung Paik and Mi-Kyoung Seo

Domestic Patents (Issued)

  • “유방암 분자아형 분류방법 및 유방암 분자아형 분류 디바이스”, 대한민국 특허 10-1966589, 2019/04/01
    발명자: 김상우, 백순명, 서미경

Last Update: June 7, 2019