March 5, 2019

We published a new paper in Nature Communications.

In this study, in collaboration with Prof. Jeong Ho Lee (KAIST), Dr. Junho Kim developed a new probabilistic model to accurately call somatic mutations that are present in a very low allele-frequency (<1%). We showed th...

January 23, 2019

We published a new paper in Leukemia.

In this study, in collaboration with Prof. Sun Och Yoon (Dept. of Pathology) Gunho Lee analyzed genomic mutations in NK- and T-cell lymphoma, which is a very rare type of lymphoma, to find characterizing somatic mutations. Especiall...

January 15, 2019

We published a new paper in Cancer Research and Treatment.

In this study, Sangwoo Kim worked with KCSG-TRIUMPH consortium to analyze the somatic mutations of Korean head and neck squamous carcinoma patients. 

"Investigating the feasibility of targeted next-generation seq...

April 1, 2018

We published a new paper in Annals of Oncology.

In this study, Sora Kim and Sangwoo Kim developed a new algorithm, Neopepsee, that predicts somatic mutation-derived neoantigens from NGS sequencing data. We used a machine learning model with 9 immunogenicty features and...

March 8, 2018

We published a new paper in PLoS ONE.

In this paper, Dr. Ka-Kyung Kim analyzed the gene expression and pathway activities in the treatment of mmLDL that affects TLR4 pathway.

"Palmitate and Minimally-Oxidized Low-Density Lipoprotein Additively Promotes Macrophage Activat...

February 19, 2018

We published a new paper in BMC Bioinformatics.

In this study, Dr. In Seok Yang and Prof. Sangwoo Kim found a differently expressed transcripts of KRAS (K-Ras4A and K-Ras4B) is associated with the prognosis of lung adenocarcinoma.

"Isoform specific gene expression analys...

November 17, 2017

We published a new paper in Lung Cancer.

In this collaborative study with Prof. Byung-Chul Cho (Severance Hospital, Dept. of Internal Medicine) Sora Kim and Sangwoo Kim analyzed genomic profiles of lung cancer patients who had a first-line EGFR-TKI (EGFR Tyrosine Kinase...

November 6, 2017

We published a new paper in Bioinformatics.

In this study, Dr. Sunguk Shin developed a new filtering method for somatic variant calling in Ion-Torrent sequencing platform, which shows a different error-profiles from conventional Illumina sequencing. The AIRVF removed pr...

October 27, 2017

We published a new paper in Scientific Reports.

In this paper, Hyeonju Son analyzed publicly reported somatic mutations in cancer to identify the uncovered bias in the usage of codons. Hyeondeok Kang and Prof. Hyun Seok Kim also joined the study.

"Somatic mutation driven...

May 31, 2017

We published a new paper in the Lecture Notes in Computer Science

In this study, Prof. Sangwoo Kim and Prof. Hojung Nam (GIST) developed a new computation framework to simulate the cellular signal transduction based on the gene/protein networks. This new framework has b...

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[Media cover] Dr. Junho Kim appeared in BRIC homepage

March 14, 2019

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